Biomarkers in occupational cancer epidemiology: considerations in study design.

Biomarkers in occupational cancer epidemiology: considerations in study design.

Epidemiologic studies of occupational groups have been central to the identification of human carcinogens. The incorporation of a biochemical component into occupational studies of cancer can expand the possibilities for identifying human carcinogens and for understanding the disease process. Two epidemiologic studies of occupation and cancer which include evaluation of biomarkers are described...

Design Considerations in Molecular Epidemiology

There is a wide range of biomarkers that can be used in population-based molecular epidemiological studies of cancer. These include biomarkers of exposure, intermediate endpoints (e.g., biomarkers of early biological effect), disease, and susceptibility (1-7) (Fig. l). Hypothesis-driven biomarkefs have been used for many years in molecular epidemiology studies of cancer (e.9., measurement of xe...

Biomarkers in Prostate Cancer Epidemiology

Understanding the etiology of a disease such as prostate cancer may help in identifying populations at high risk, timely intervention of the disease, and proper treatment. Biomarkers, along with exposure history and clinical data, are useful tools to achieve these goals. Individual risk and population incidence of prostate cancer result from the intervention of genetic susceptibility and exposu...

Round Table Advances in Occupational Cancer Occupational Cancer Epidemiology

Considerations Concerning the Epidemiology of Occupational Dermatoses

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/ 3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Our erudite colleague, in his Letter to the Editor, has made a valiant effort to demonstrat...